An unfortunatly long review (By my stadards)
Casandra is a girl. I know you've gotten a ton of reviews saying this, but I have plenty evidence.
#1: Tom Fulp himself stated that Casandra is a girl possessed by a male alien. It's as simple as that. I could stop there, but I like rambling.
#2: For God's sake, her NAME is CASANDRA. I feel bad for any male being carrying the name Cassandra.
#3: Cyclops said "Casandra must have a crush on you"
#4: Lipstick and nailpolish. Yes, I know she's goth, but boys that wear make-up are emo, not goth. (In a usual sense, anyways.)
#5: When Pico Roulette worked, Casandra... well, look it up. It makes me sick typing it.
As for the actual game, it's hard, but I enjoyed it. I basically destroyed my keyboard to get past Cyclops, and I have yet to pass Hanzou.